{"product_id":"ambrox-super-dsm-firmenich","title":"Ambrox® Super (dsm-firmenich) | Biotech Ambroxan","description":"\u003ch2\u003eAmbrox® Super – dsm-firmenich\u003c\/h2\u003e\n\u003cp\u003eAmbrox® Super is the pure (−)-enantiomer of Ambrox, the key odorant of grey ambergris. Firmenich (today dsm-firmenich) decoded its structure in the 1930s; since 2016, Ambrox® Super has been made through white biotechnology – with 100% renewable carbon and readily biodegradable. The same molecule is sold under names such as Ambroxan, Ambrofix™ or Orcanox.\u003c\/p\u003e\n\n\u003ch2\u003eOdor Profile\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e“Extremely powerful and elegant ambery odor with a musky, woody tonality” – the manufacturer’s description\u003c\/li\u003e\n\u003cli\u003eOfficial descriptors: Ambery, Woody\u003c\/li\u003e\n\u003cli\u003eCompared with Cetalox®, per dsm-firmenich “more natural, more animalic and closer to the original ambergris”\u003c\/li\u003e\n\u003cli\u003ePerceptible on a blotter for about a month (tenacity 12 on the manufacturer’s scale)\u003c\/li\u003e\n\u003cli\u003eCrystalline powder\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eRole in the Formula\u003c\/h2\u003e\n\u003cp\u003eAmbrox® Super sits in the heart and base, yet it works from the first spray into the drydown: dsm-firmenich describes it as highly diffusive, with an amber effect that runs through the whole composition. It clings exceptionally to hair, skin and fabric – in shampoo, shower gel, soap and fabric softener it earns the top rating on the manufacturer’s scale. For fine fragrance the manufacturer recommends 0.6–3%.\u003c\/p\u003e\n\u003cp\u003eStereochemistry and production separate it from its sibling \u003ca href=\"\/en\/products\/ambrox-dl-dsm-firmenich\"\u003eAmbrox® DL\u003c\/a\u003e: Super is the single (−)-enantiomer from the fermenter (log P 6.85), DL the racemate (CAS 3738-00-9) from the chemical synthesis developed in 1988. The same molecule as Super, but from other houses, is available here as \u003ca href=\"\/en\/products\/ambrofix-givaudan-ambroxan\"\u003eAmbrofix™ (Givaudan)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/ambermor-iff-ambroxan\"\u003eAmberMor® (IFF)\u003c\/a\u003e and \u003ca href=\"\/en\/products\/ambroxide-cryst-symrise\"\u003eAmbroxide Cryst. (Symrise)\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eUse in Perfumery\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFine fragrance: 0.6–3%\u003c\/li\u003e\n\u003cli\u003eShampoo: 0.05–0.1% · Shower gel: 0.1–0.7% · Soap: 0.06–0.3%\u003c\/li\u003e\n\u003cli\u003eLaundry detergent: 0.2–0.8% · Fabric softener: 0.2–0.8%\u003c\/li\u003e\n\u003cli\u003eAll-purpose cleaner: 0.02–0.03% · Candles: 0.02–0.1%\u003c\/li\u003e\n\u003cli\u003eSubstantivity (manufacturer’s scale): shampoo 4\/4, shower gel 4\/4, soap 4\/4, detergent 3\/4, softener 4\/4, candle 3\/3\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003ePractical Notes: Dissolving, Storage, Pairing\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDissolving:\u003c\/strong\u003e Insoluble in water, readily soluble in ethanol. For precise work at the organ, a 10% solution in ethanol is recommended.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Cool, dry, protected from light and tightly closed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePairing:\u003c\/strong\u003e Fits amber, woody and musk accords. As a heart-to-base material it carries a composition from the opening to the finish.\u003c\/p\u003e\n\n\u003ch2\u003eFrom Ambergris to White Biotechnology\u003c\/h2\u003e\n\u003cp\u003eFirmenich’s ambergris research goes back to the 1930s – to a research environment honoured in 1939 with the Nobel Prize in Chemistry for Leopold Ružička. In 2016 came the step into the fermenter: clary sage enzymes produce the precursor sclareol, and green chemistry takes it on to (−)-Ambrox. According to the manufacturer, independence from sage harvests means consistent quality and reliable availability; the green-chemistry score is 50–70%. The full story is told on our encyclopedia page \u003ca href=\"\/en\/pages\/ambrox-super\"\u003eAmbrox® Super\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eSafety Information\u003c\/h2\u003e\n\u003cp\u003eAccording to the manufacturer's data (Firmenich\/dsm-firmenich), Ambrox® Super (CAS 6790-58-5) is not classified as hazardous – no pictogram, no signal word, no H-statements. No IFRA Standard exists. According to the manufacturer, readily biodegradable.\u003c\/p\u003e\n\n\u003ch2\u003ePhysico-Chemical Properties\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\u003ctd\u003eManufacturer\u003c\/td\u003e\u003ctd\u003edsm-firmenich\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eProduct name\u003c\/td\u003e\u003ctd\u003eAmbrox® Super\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eProduct code\u003c\/td\u003e\u003ctd\u003e909158\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eFragrance family\u003c\/td\u003e\u003ctd\u003eAmbery (descriptors: Ambery, Woody)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eRole in perfumery\u003c\/td\u003e\u003ctd\u003eHeart and base note\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003ePhysical form\u003c\/td\u003e\u003ctd\u003eCrystalline powder\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eMolecular formula\u003c\/td\u003e\u003ctd\u003eC16H28O\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eMolecular weight\u003c\/td\u003e\u003ctd\u003e236.4 g\/mol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eCAS No.\u003c\/td\u003e\u003ctd\u003e6790-58-5 ((−)-enantiomer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eEC No.\u003c\/td\u003e\u003ctd\u003e229-861-2\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eREACH registration\u003c\/td\u003e\u003ctd\u003e01-2120070784-50\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eLog P\u003c\/td\u003e\u003ctd\u003e6.85\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eWater solubility\u003c\/td\u003e\u003ctd\u003eInsoluble (soluble in ethanol)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eDensity\u003c\/td\u003e\u003ctd\u003e0.939 (literature value)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eRefractive index\u003c\/td\u003e\u003ctd\u003e1.48 (literature value)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eMelting point\u003c\/td\u003e\u003ctd\u003eca. 75 °C (literature value)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eFlash point\u003c\/td\u003e\u003ctd\u003e\u0026gt; 100 °C\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eVapour pressure\u003c\/td\u003e\u003ctd\u003e0.29 Pa at 20 °C (manufacturer data)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eLongevity on blotter\u003c\/td\u003e\u003ctd\u003eca. 1 month\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eUse level\u003c\/td\u003e\u003ctd\u003eFine fragrance 0.6–3%\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eRenewable carbon\u003c\/td\u003e\u003ctd\u003e100%\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eBiodegradability\u003c\/td\u003e\u003ctd\u003eReadily biodegradable\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003ePatent\u003c\/td\u003e\u003ctd\u003eWO 2009\/101126 (Firmenich, 2008 – precursor sclareol) · \u003ca href=\"\/en\/pages\/patentbibliothek#p-ambrox-super\"\u003ePatent Library\u003c\/a\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\n\u003ch2\u003eFAQ\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Ambrox® Super?\u003c\/strong\u003e\u003cbr\u003eThe pure (−)-enantiomer of Ambrox (CAS 6790-58-5), made by biotechnology at dsm-firmenich – the house that discovered the molecule in ambergris.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs Ambrox® Super the same as Cetalox®?\u003c\/strong\u003e\u003cbr\u003eNo. Cetalox® and Ambrox® DL are racemates (CAS 3738-00-9). The warm, animalic facet belongs to the (−)-enantiomer – which is why, according to the manufacturer, Super smells more natural and closer to real ambergris.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do I dose Ambrox® Super?\u003c\/strong\u003e\u003cbr\u003eIn fine fragrance 0.6–3%; from about 2% it clearly shapes the base. Best worked from a 10% solution in ethanol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAre there IFRA restrictions or hazard warnings?\u003c\/strong\u003e\u003cbr\u003eNo. There is no IFRA Standard for CAS 6790-58-5, and according to the manufacturer's data the substance is not classified as hazardous.\u003c\/p\u003e\n\n\u003ch2\u003eHazard Information (CLP Labelling)\u003c\/h2\u003e\n\u003cdiv style=\"border:1px solid #d0d0d0;border-radius:8px;padding:16px;max-width:640px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eNot classified as hazardous\u003c\/strong\u003e under Regulation (EC) No 1272\/2008 (CLP), according to the manufacturer's data. No pictogram, signal word or H-statement required.\u003c\/p\u003e\n\u003cp style=\"font-size:0.85em;color:#666;\"\u003eThe labelling on the container is authoritative.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003ch2\u003eImportant Notice\u003c\/h2\u003e\n\u003cp\u003eThis product is a perfumery raw material intended exclusively for fragrance development, creative experimentation, education and the study of perfumery materials.\u003c\/p\u003e\n\u003cp\u003eIt is not a finished cosmetic product.\u003c\/p\u003e\n\u003cp\u003ePlease use responsibly.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en\/pages\/ambroxan-vergleich\"\u003eComparison of all Ambroxan versions →\u003c\/a\u003e\u003c\/p\u003e","brand":"dsm-firmenich","offers":[{"title":"10 g","offer_id":53695321604432,"sku":"AMBXS-10","price":24.0,"currency_code":"EUR","in_stock":true},{"title":"20 g","offer_id":53697368654160,"sku":"AMBXS-20","price":42.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53697368686928,"sku":"AMBXS-50","price":90.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53697368719696,"sku":"AMBXS-100","price":156.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53713481204048,"sku":null,"price":330.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0902\/1341\/7296\/files\/AMBROXSUPER.jpg?v=1790429849","url":"https:\/\/laborammeer.de\/en\/products\/ambrox-super-dsm-firmenich","provider":"Labor am Meer","version":"1.0","type":"link"}