{"product_id":"ambroxide-cryst-symrise","title":"Ambroxide Cryst. (Symrise) | Ambroxan","description":"\u003ch2\u003eAmbroxide Cryst. – Symrise\u003c\/h2\u003e\n\u003cp\u003eAmbroxide Cryst. is Symrise’s Ambroxan – the same CAS number 6790-58-5 as \u003ca href=\"\/en\/products\/ambrofix-givaudan-ambroxan\"\u003eAmbrofix™ (Givaudan)\u003c\/a\u003e, \u003ca href=\"\/en\/products\/ambermor-iff-ambroxan\"\u003eAmberMor® (IFF)\u003c\/a\u003e and \u003ca href=\"\/en\/products\/ambrox-super-dsm-firmenich\"\u003eAmbrox® Super (dsm-firmenich)\u003c\/a\u003e. Symrise sells it without a fantasy name, under its chemical designation: off-white to white crystals, at least 99% purity, 100% renewable carbon.\u003c\/p\u003e\n\n\u003ch2\u003eOdor Profile\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eOfficial descriptors: “Ambery, Amber, Wood” – ambery with a woody tonality\u003c\/li\u003e\n\u003cli\u003eAccording to Symrise, a clean, substantive amber note\u003c\/li\u003e\n\u003cli\u003ePositioned by the manufacturer as a “lead substance for ambery creations”\u003c\/li\u003e\n\u003cli\u003eBase note and fixative with pronounced tenacity on skin and fabric\u003c\/li\u003e\n\u003cli\u003eOff-white to white crystals\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eRole in the Formula\u003c\/h2\u003e\n\u003cp\u003eAmbroxide carries the amber character of a formula from the drydown into the long-wear phase. Symrise recommends 0.1–2%: at low levels it adds warmth and depth in the background; dosed higher, it becomes the amber theme itself.\u003c\/p\u003e\n\u003cp\u003eChemically it does not differ from Ambrofix™, AmberMor® and Ambrox® Super – what separates the products is the production route, not the molecule. All versions side by side: \u003ca href=\"\/en\/pages\/ambroxan\"\u003eAmbroxan: all versions compared\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eUse in Perfumery\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFine fragrance: 0.1–2% in the concentrate\u003c\/li\u003e\n\u003cli\u003eTested by Symrise in eau de toilette (4.0%), soap (1.2%) and deodorant (1.0%), among others\u003c\/li\u003e\n\u003cli\u003eStable even in chlorine-containing media – useful for functional applications\u003c\/li\u003e\n\u003cli\u003eClassic role: amber base, replacement for animal ambergris, backbone of woody-amber fragrances\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003ePractical Notes: Dissolving, Storage, Pairing\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDissolving:\u003c\/strong\u003e Practically insoluble in water, readily soluble in ethanol. For formula work, prepare a 10–20% pre-dilution in ethanol or DPG – it lets you weigh the low use range accurately.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Cool, dry, protected from light and tightly closed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePairing:\u003c\/strong\u003e Woody materials are the natural partners – as the official descriptors “Amber” and “Wood” already suggest.\u003c\/p\u003e\n\n\u003ch2\u003eFrom Holzminden\u003c\/h2\u003e\n\u003cp\u003eThe route is classic: sclareol from clary sage → sclareolide → ambradiol → ambroxide. All the carbon comes from the plant, hence the renewable factor of 100%. In 2018 Symrise patented a one-step process that oxidises sclareol directly to sclareolide with ozone. The manufacturer is Symrise AG in Holzminden, formed in 2003 from Haarmann \u0026amp; Reimer and Dragoco. More in our encyclopedia: \u003ca href=\"\/en\/pages\/ambroxide-symrise\"\u003eAmbroxide Cryst. – Ambroxan from Holzminden\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eSafety Information\u003c\/h2\u003e\n\u003cp\u003eAccording to the ECHA C\u0026amp;L Inventory, CAS 6790-58-5 is not classified as hazardous – no pictogram, no signal word, no H-statements. No IFRA Standard exists. At 71%, the material counts as readily biodegradable.\u003c\/p\u003e\n\n\u003ch2\u003ePhysico-Chemical Properties\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\u003ctd\u003eManufacturer\u003c\/td\u003e\u003ctd\u003eSymrise AG, Holzminden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eProduct name\u003c\/td\u003e\u003ctd\u003eAmbroxide Cryst.\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eProduct code\u003c\/td\u003e\u003ctd\u003e600304\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eFragrance family\u003c\/td\u003e\u003ctd\u003eAmber (Ambery, Amber, Wood)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eRole in perfumery\u003c\/td\u003e\u003ctd\u003eBase note, fixative\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003ePhysical form\u003c\/td\u003e\u003ctd\u003eOff-white to white crystals\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003ePurity\u003c\/td\u003e\u003ctd\u003e≥ 99% (GC)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eMolecular formula\u003c\/td\u003e\u003ctd\u003eC16H28O\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eMolecular weight\u003c\/td\u003e\u003ctd\u003e236.4 g\/mol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eCAS No.\u003c\/td\u003e\u003ctd\u003e6790-58-5\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eEC No.\u003c\/td\u003e\u003ctd\u003e229-861-2\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eREACH registration\u003c\/td\u003e\u003ctd\u003e01-2120070784-50\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eLog P\u003c\/td\u003e\u003ctd\u003e4.76\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eWater solubility\u003c\/td\u003e\u003ctd\u003ePractically insoluble; soluble in ethanol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eDensity\u003c\/td\u003e\u003ctd\u003e0.939 (literature value)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eRefractive index\u003c\/td\u003e\u003ctd\u003eca. 1.48 (literature value)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eMelting point\u003c\/td\u003e\u003ctd\u003eca. 75 °C (literature value)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eBoiling point\u003c\/td\u003e\u003ctd\u003e276.8 °C\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eFlash point\u003c\/td\u003e\u003ctd\u003e\u0026gt; 100 °C\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eUse level\u003c\/td\u003e\u003ctd\u003e0.1–2%\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eRenewable carbon\u003c\/td\u003e\u003ctd\u003e100%\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003eBiodegradability\u003c\/td\u003e\u003ctd\u003e71% – readily biodegradable\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003ctd\u003ePatent\u003c\/td\u003e\u003ctd\u003eUS 11,572,352 B2 (Symrise, priority 2018, active – precursor sclareolide) · \u003ca href=\"\/en\/pages\/patentbibliothek#p-ambroxide\"\u003ePatent Library\u003c\/a\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\n\u003ch2\u003eFAQ\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eIs Ambroxide Cryst. Ambroxan?\u003c\/strong\u003e\u003cbr\u003eYes. “Ambroxan” is the common name for the molecule with CAS number 6790-58-5. Givaudan calls it Ambrofix™, IFF AmberMor®, Symrise simply Ambroxide Cryst.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy does it have no brand name?\u003c\/strong\u003e\u003cbr\u003eSymrise sells off-patent molecules under their chemical names; brand names are reserved for its own developments such as \u003ca href=\"\/en\/products\/ambrocenide-cryst-symrise\"\u003eAmbrocenide®\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do I dose Ambroxide Cryst.?\u003c\/strong\u003e\u003cbr\u003e0.1–2% in the concentrate, best from a pre-dilution in ethanol or DPG.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes ambroxide occur in nature?\u003c\/strong\u003e\u003cbr\u003eYes – in grey ambergris it forms through oxidation of the triterpene ambrein. Industrially it is made from sclareol of clary sage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAre there IFRA restrictions or hazard warnings?\u003c\/strong\u003e\u003cbr\u003eNo. There is no IFRA Standard, and according to the ECHA C\u0026amp;L Inventory the substance is not classified as hazardous.\u003c\/p\u003e\n\n\u003ch2\u003eHazard Information (CLP Labelling)\u003c\/h2\u003e\n\u003cdiv style=\"border:1px solid #d0d0d0;border-radius:8px;padding:16px;max-width:640px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eNot classified as hazardous\u003c\/strong\u003e under Regulation (EC) No 1272\/2008 (CLP), based on the ECHA C\u0026amp;L Inventory. No pictogram, signal word or H-statement required.\u003c\/p\u003e\n\u003cp style=\"font-size:0.85em;color:#666;\"\u003eThe labelling on the container is authoritative.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003ch2\u003eImportant Notice\u003c\/h2\u003e\n\u003cp\u003eThis product is a perfumery raw material intended exclusively for fragrance development, creative experimentation, education and the study of perfumery materials.\u003c\/p\u003e\n\u003cp\u003eIt is not a finished cosmetic product.\u003c\/p\u003e\n\u003cp\u003ePlease use responsibly.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en\/pages\/ambroxan-vergleich\"\u003eComparison of all Ambroxan versions →\u003c\/a\u003e\u003c\/p\u003e","brand":"Symrise","offers":[{"title":"10 g","offer_id":53695336350032,"sku":"AMBXD-10","price":33.0,"currency_code":"EUR","in_stock":true},{"title":"20 g","offer_id":53697368818000,"sku":"AMBXD-20","price":57.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53697368850768,"sku":"AMBXD-50","price":122.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53697368883536,"sku":"AMBXD-100","price":211.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53842012963152,"sku":"AMBXD-250","price":429.0,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53842012995920,"sku":"AMBXD-500","price":750.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0902\/1341\/7296\/files\/Ambrofix_2.jpg?v=1790429103","url":"https:\/\/laborammeer.de\/en\/products\/ambroxide-cryst-symrise","provider":"Labor am Meer","version":"1.0","type":"link"}