Symrise
Ambrocenide® Cryst. (Symrise) | Woody-Amber Booster
Ambrocenide® Cryst. (Symrise) | Woody-Amber Booster
Couldn't load pickup availability
Ambrocenide® Cryst. – Symrise
Ambrocenide® is a woody-amber booster from Symrise's cedarwood chemistry – not an Ambroxan, but an acetal with a chemistry of its own. Its odor threshold is 0.0013 µg/l of air: even traces audibly change a formula. Symrise supplies the pure substance as pale-white to white crystals with a GC purity of at least 99%.
Odor Profile
- Official descriptors: “Ambery, Wood, Amber” – ambery-woody, dry, assertive
- “Powerful and long-lasting top to base booster” – per the manufacturer, a strong, long-lasting amplifier from top to base note
- Lends power to woody and amber accords and volume to floral heart notes
- According to Symrise, makes musk notes perceptible as early as the top note
Role in the Formula
Ambrocenide is not a classic base material but an amplifier: it lifts woody-amber structures, floral heart notes and musk across the whole evolution of a fragrance. Symrise gives a use range from traces to 2%, the patent typical amounts of 0.05–2 wt%. For the intense woody-amber style of many niche and designer fragrances, it is the right power component.
On the amber shelf it complements the Ambroxan family – such as Ambroxide Cryst. from the same house or Ambrofix™ (Givaudan) – but chemically it is something else: an acetal from α-cedrene. Its synergy with musk notes, which it pushes forward, is documented.
Use in Perfumery
- Fine fragrance: traces to 2% (crystals) in the concentrate
- Tested by Symrise in eau de toilette (4.0% fragrance oil) as well as soap, deodorant, shampoo, fabric softener and detergent
- Olfactorily stable, including in chlorine-containing media
- Besides the crystals (no. 600199), Symrise offers a 10% solution in DPG (no. 100215) – with this material, dilution is the norm
Practical Notes: Dissolving, Storage, Pairing
Dissolving: Always work from a pre-dilution; 1% or 10% in DPG or ethanol is common. Undiluted, the trace range cannot be weighed sensibly.
Storage: Cool, dry, protected from light and tightly closed. The material contains no stabiliser.
Pairing: Per the manufacturer: woody and amber accords (power), floral heart notes (volume) and musk (lift into the top note).
From Cedarwood Chemistry
According to the Symrise patent, Ambrocenide is made from α-cedrene, a sesquiterpene of cedarwood oil: via cedrene epoxide and cedrane diols, acetalisation with dimethoxypropane yields the finished molecule. Stereochemistry is decisive – the (4aR,5R,7aS,9R) stereoisomer smells considerably stronger than the other diastereomers, hence the low use levels. The renewable carbon share is 83.3%. Ambrocenide® is a registered trademark of Symrise AG, Holzminden.
Safety Information
According to the ECHA C&L Inventory, Ambrocenide is classified with GHS07 and the signal word “Warning”: H315 (causes skin irritation) and H319 (causes serious eye irritation). Wear protective gloves and safety glasses when handling the crystals. No IFRA Standard exists.
Physico-Chemical Properties
| Manufacturer | Symrise AG, Holzminden |
| Product name | Ambrocenide® Cryst. |
| Product code | 600199 (crystals); 100215 (10% in DPG) |
| Fragrance family | Amber, woody (Ambery, Wood, Amber) |
| Role in perfumery | Booster from top to base note |
| Physical form | Pale-white to white crystals |
| Purity | ≥ 99% (GC) |
| Molecular formula | C18H30O2 |
| Molecular weight | 278.4 g/mol |
| CAS No. | 211299-54-6 |
| EC No. | 427-580-1 |
| REACH registration | 01-0000017394-68 |
| Log P | 6 |
| Boiling point | 309.2 °C |
| Flash point | > 100 °C |
| Odor threshold | 0.0013 µg/l air |
| Use level | Traces to 2% (crystals) |
| Renewable carbon | 83.3% |
| Patent | EP 0 857 723 B1 / EP 3 672 692 B1 (Dragoco/Symrise, priority 1997 (expired) and 2017 (active)) · Patent Library |
FAQ
What is Ambrocenide?
A very strong woody-amber booster by Symrise (CAS 211299-54-6) that amplifies ambery, woody, floral and musk notes across the whole fragrance evolution.
Is Ambrocenide the same as Ambroxan?
No. Despite the similar name it is a different molecule: an acetal from α-cedrene. Both serve the amber theme but differ completely in chemistry and strength.
How do I dose Ambrocenide?
In traces up to at most 2% (crystals), always from a pre-dilution of 1% or 10% in DPG.
Why is Ambrocenide so strong?
According to the Symrise patent, the (4aR,5R,7aS,9R) stereoisomer produced smells considerably stronger than the other diastereomers.
Is Ambrocenide hazardous or IFRA-restricted?
It is classified as a skin and eye irritant (H315, H319) – use gloves and safety glasses. No IFRA Standard exists.
Hazard Information (CLP Labelling)
Signal word: Warning
H-statements:
H315 – Causes skin irritation.
H319 – Causes serious eye irritation.
P-statements:
P264 – Wash hands thoroughly after handling.
P280 – Wear protective gloves/eye protection.
P302+P352 – IF ON SKIN: Wash with plenty of water.
P305+P351+P338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P317 – If skin irritation occurs: Get medical advice.
P337+P317 – If eye irritation persists: Get medical advice.
P362+P364 – Take off contaminated clothing and wash it before reuse.
Classification per the ECHA C&L Inventory; the labelling on the container is authoritative.
Important Notice
This product is a perfumery raw material intended exclusively for fragrance development, creative experimentation, education and the study of perfumery materials.
It is not a finished cosmetic product.
Please use responsibly.
