Patent Library
Patent Library – the patents behind the aroma materials
Behind many molecules in our range there is a patent: who invented it, when, and what exactly was protected. Here we have collected the patents we have verified ourselves for our materials – each with a link to the original document.
How to read the entries
- Priority is the date of the first filing, grant the date on which the patent was issued.
- Links: the patent number opens Espacenet, the official database of the European Patent Office. “Full text” opens the document on Google Patents for easier reading.
- Status as stated by Google Patents, or roughly 20 years from filing. This is for orientation only, not legal advice.
- Not every patent protects the molecule itself. Some cover a manufacturing process, a precursor or a use – this is noted in each case.
Contents
- Wood and amber
- Musk
- Floral, fresh, marine
- Lactones and warm notes
- Fixation
- Materials without a patent found
1. Wood and amber
ISO E Super®
US 3,911,018 (full text) · IFF · Inventors: J. B. Hall, J. M. Sanders · Priority 27 Feb 1973 · granted 1975 · expired
Octahydro-tetramethyl-acetonaphthones and their preparation – the compound class of ISO E Super.
US 3,929,677 (full text) · IFF · Inventors: J. B. Hall, J. M. Sanders · Priority 21 Jan 1974 · granted 1975 · expired
Perfume compositions containing predominantly a single isomer of octahydro-tetramethyl-acetonaphthone.
Javanol™
EP 0 801 049 B1 (full text), US 5,929,291 (full text) · Givaudan · Inventors: Bajgrowicz, Fráter · Priority 9 Apr 1996 · granted 1999 (US), 2001 (EP) · expired
Cyclopentanebutanol derivatives with a cyclopropane ring as odorants, derived from campholenic aldehyde.
Ebanol™
US 4,696,766 (full text) · Givaudan Corp. · Inventor: R. E. Naipawer · Priority 19 Mar 1986 · granted 1987 · expired
Isomer mixtures of 3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol containing at least 10 % of the (2R*,3S*)-(E) isomer.
Sandalore™
US 4,052,341 (full text) · Givaudan Corp. · Inventors: R. E. Naipawer, Easter · Priority 29 Apr 1976 · granted 1977 · expired
The Sandalore alcohol and perfume compositions containing more than 60 % of this compound.
Norlimbanol®
US 4,252,986 (full text) (compound), US 4,313,855 (full text) (use as fixative) · Dragoco · Inventors: Klein, Rojahn · Priority 22 Feb 1978 · granted 1981/1982 · expired
1-(2,2,6-Trimethylcyclohexyl)hexan-3-ol – the same molecule Dragoco marketed as Timberol. We have not found a separate Firmenich patent on Norlimbanol.
Ambrocenide® Cryst.
EP 0 857 723 B1 (full text) · Dragoco (now Symrise) · Inventors: Pickenhagen, Schatkowski · Priority 6 Feb 1997 · granted 2002 · expired
Cyclic cedrene acetals – the compound class of Ambrocenide.
EP 3 672 692 B1 (full text) · Symrise · Inventors: Eh, Lambrecht · Priority 25 Aug 2017 · granted 2023 · active
Mixtures with enantiomerically pure Ambrocenide in which the weaker isomer is below 0.01 %.
Ambrofix™
US 10,844,412 B2 (full text) · Givaudan · Inventors: Sanhaji, Rousseaux, Noel, Eichhorn · Priority 22 Apr 2016 · granted 2020 · active
Solid, crystalline form of (−)-Ambrox obtained by bioconversion of homofarnesol with an enzyme (squalene-hopene cyclase). Part of a larger patent family.
Ambrox® Super
WO 2009/101126 A1 (full text) · Firmenich · Inventor: M. Schalk · Priority 15 Feb 2008 · precursor
Enzymatic production of sclareol, the plant-derived starting material for Ambrox. Not a patent on Ambrox itself.
Ambroxide Cryst.
US 11,572,352 B2 (full text) (published as US 2021/0300885 A1) · Symrise · Inventors: Hölscher et al. · Priority 23 Aug 2018 · granted 2023 · active · precursor
One-step oxidation of sclareol with ozone to sclareolide – a precursor on the route to Ambroxide.
Sylvamber™
According to the manufacturer's safety data sheet, Sylvamber is listed under the same REACH registration as OTNE, the molecule of ISO E Super. The substance patents are therefore those of ISO E Super: US 3,911,018 and US 3,929,677 (IFF, expired). We have not found a separate patent on Sylvamber.
Timbersilk™
Timbersilk is a single isomer of OTNE (CAS 68155-66-8). The substance class is described by the patents of ISO E Super (IFF, expired); we have not found a separate patent on the enriched isomer.
Ambermax™
US 7,550,417 B2 (full text) · Givaudan · Inventor: Bajgrowicz, Frank · Priority 14 Sep 2005 · granted 2009 · term according to Google Patents until September 2026
Tri- and tetracyclic terpenoid alcohols and ethers as amber odorants, including the two isomers 2-(2,2,7,7-tetramethyltricyclo[6.2.1.0¹,⁶]undec-5-en-5-yl)- and -undec-4-en-5-yl)propan-1-ol – the molecules of Ambermax.
The original Ambrox synthesis was developed at Firmenich in 1950 (Stoll, Hinder). We were unable to verify a patent number for it.
2. Musk
Galaxolide (HHCB)
US 3,360,530 (full text) · IFF · Inventors: Heeringa, Beets · Priority 23 Jul 1962 (GB) · granted 1967 · expired
Tricyclic isochromans with a musk odour – the compound class of Galaxolide.
Habanolide®
EP 0 424 787 B1 (full text) · Firmenich · Inventors: Fankhauser, Fantini · Priority 27 Oct 1989 · granted 1996 · expired 2010
Use of trans-pentadec-11/12-en-15-olides as odorants – including Habanolide. The ring has 16 members; "pentadecenolide" counts only the carbon atoms.
Globalide®
WO 2016/005361 A1 (full text) · Symrise · Inventors: Hölscher et al. · Priority 7 Jul 2014
Isomer mixtures (E/Z) of unsaturated macrocyclic musk compounds in specific ratios. We have not found a patent on the molecule itself.
Muscenone® Delta
US 5,354,735 (full text) · Firmenich · Inventors: Demole, Mahaim, Blanc · Priority 30 Jul 1992 · granted 1994 · expired
Use of 3-methylcyclopentadec-5-en-1-one as an odorant with a nitro-musk-like character.
Helvetolide®
US 5,166,412 (full text), EP 0 472 966 B1 (full text) · Firmenich · Inventors: Giersch, Schulte-Elte, Mahaim · Priority 28 Aug 1990 · granted 1992 (US), 1994 (EP) · expired
Esters with a 3,3-dimethylcyclohexyl or 3,3-dimethylcyclopentyl group – the compound class of Helvetolide. The trade name does not appear in the document.
Ambrettolide
US 3,681,395 (full text) · IFF · Inventors: Mookherjee, Taylor · Priority 11 Mar 1970 · granted 1972 · expired · process
Multi-step synthesis route to Ambrettolide starting from 1,9-cyclohexadecadiene.
Velvione – related structure
US 3,923,699 (full text) · Takasago · Inventors: Komatsu et al. · Priority 29 Dec 1970 · granted 1975 · expired
Musk compositions containing cyclohexadec-5-enone. Not a patent on Velvione itself, but its structural prehistory.
3. Floral, fresh, marine
Hedione®
US 3,158,644 (full text) · Firmenich · Inventors: Demole, Lederer · Priority 25 Feb 1960 (CH) · granted 1964 · expired
Alkyl esters of 2-alkyl-3-oxo-cycloalkylacetic acids – the compound class to which methyl dihydrojasmonate belongs.
Hedione® HC
US 3,978,108 (full text) · Roure Bertrand Fils et Justin Dupont · Inventors: Teisseire, Plattier · Priority 23 Dec 1970 · granted 1976 · expired
Substantially pure cis-methyl dihydrojasmonate; a dependent claim specifies at least 90 % cis.
US 6,455,460 B1 (full text) · Firmenich · Inventors: Dobbs, Vanhessche, Rautenstrauch · Priority 20 May 1997 · granted 2002 · expired
Ruthenium catalysts for the asymmetric hydrogenation to (+)-cis-Hedione – the route to Paradisone.
Helional®
US 3,008,968 (full text) · IFF · Inventors: Beets, van Essen · Priority 11 Feb 1958 (GB) · granted 1961 · expired · process
Preparation of 2-methyl-3-(3,4-methylenedioxyphenyl)propanal by partial hydrogenation.
Calone
US 3,517,031 (full text) · Chas. Pfizer & Co. · Inventors: Beereboom, Cameron, Stephens · Priority 15 Aug 1966 · granted 1970 · expired
Benzodioxepinones as flavour and fragrance materials – the compound class of Calone.
Ultrazur™
US 9,708,570 B2 (full text) · Givaudan · Inventors: Goeke, Kraft, Zou · Priority 28 Jun 2013 · granted 2017 · active
Meta-substituted 3-phenylpropanals as watery-marine odorants. The trade name Ultrazur does not appear in the document; the attribution comes from the technical literature.
Paradisamide™
US 7,169,748 B2 (full text) (EP 1 399 413) · Quest International (now Givaudan) · Inventors: Swift, Yarwood · Priority 25 Jun 2001 · granted 2007 · expired
N-aryl amides as odorants; as a preferred compound the document names 2-ethyl-N-methyl-N-(3-methylphenyl)butanamide – Paradisamide. The patent comes from Quest, which was acquired by Givaudan in 2007.
4. Lactones and warm notes
Methyl Laitone
US 4,519,944 (full text) · Givaudan Corp. · Inventors: Dahill, Purzycki, Golle · Priority 25 Aug 1982 · granted 1985 · expired
Spirolactones as odorants, including 8-methyl-1-oxaspiro[4.5]decan-2-one.
Cashmeran®
US 3,773,836 (full text) · IFF · Inventor: J. B. Hall · Priority 18 Aug 1969 · granted 1973 · expired
Pentamethyl-dihydroindanones and their preparation – the Cashmeran ketone.
5. Fixation
Glucam™ P-20
US 4,264,478 (full text), US 4,324,703 (full text) · Amerchol · Inventor: A. Seldner · Priority 30 Oct 1978 · granted 1981/1982 · expired
Alkoxylated methyl glucosides as fixatives for fragrances – process and composition.
Fixative or solvent – a more recent concept
WO 2021/247838 A1 (full text) · Coty · Priority 5 Jun 2020
Fragrance compositions with an odourless "modulator" intended to change how the fragrance materials are perceived.
6. Materials without a patent found
For the following materials we have not found a patent we could clearly attribute: Cetalor, Silvanone Supra, Oxyoctaline Formate, Isobutavan, Rum Acetal, Vanillin PG Acetal and Coumarone. For captive molecules, manufacturers rarely publish which patent belongs to which trade name. Exaltolide® goes back to the macrocycle chemistry of the 1920s; there is no patent relevant to it today.
The library grows with our range. All information comes from the linked patent documents.